In response to Richard Jones’ book review, I said: So according to Jones, we can’t trust anthropologists to describe foragers they’ve met, we can’t trust economics when tech changes society, and familiar design principles fail for understanding brains and tiny chemical systems. Apparently only his field, physics, can be trusted well outside current experience. In reply, I say I’d rather rely on experts in each field, relative to his generic skepticism. Brain scientists see familiar design principles as applying to brains, even when designed by evolution, economists see economics as applying to past and distant societies with different tech, and anthropologists think they can understand cultures they visit.